Соматизация

Longitudinal qEEG changes correlate with clinical outcomes in patients with somatic symptom disorder

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У пациентов с соматизацией высокая альфа, низкие бета 2 (25–30 Hz) и гамма. После успешной психотерапии бета 2 и гамма выше.

SSD is heterogeneous and complex, and symptoms vary widely

the underlying mechanism remains unclear

In addition, we found that SSD patients exhibited lower gamma power in all five cerebral regions than the NCs. Gamma activity plays a key role in the mediation of local sensory and attentional-processing signals [33,34]. Lower gamma activity may suggest an altered response to sensory stimuli.

Compared to the NC group, greater frontal, temporal, and parietal alpha power was exhibited by the SSD group. The alpha rhythm predominates during rest with the eyes closed; an increased alpha power is commonly taken to indicate restfulness. However, alpha power does not merely reflect the resting state, rather, it is a complicated form of brain activity that varies depending on whether the focus is on external or internal stimuli. The power across the alpha band is negatively associated with regional cortical activity; increased alpha activity indicates local inhibition [27]. When processing external stimuli, the corresponding brain regions become active (blocked alpha activity) while others are inhibited (enhanced alpha activity) [28,29]. Conversely, when the focus is on internal stimuli, i.e., mental imagery, imagination, and internal attention, alpha activity increases [28]; this has been interpreted as the active inhibition required for “internally driven mental operations” [28,30]. Therefore, we suggest that the global enhancement in alpha power evident in the SSD group may reflect over-selective attention to internal body signals and related thoughts, and thus a decreased response to the external world. This is consistent with previous reports showing that patients with SSD tend to concentrate more on bodily sensations and inner stimuli, and have difficulty switching their attention to external stimuli [3,6]. In addition, the alpha power exhibited particularly strong negative correlations with resting brain activity in frontal and parietal areas [31] which are associated with attentional processing [32]. This suggests that the higher alpha powers in these areas may reflect decreased attention.